Photopheresis therapy are being conducted to investigate its potential benefits in the treatment



 As the autoimmune disease becomes more common around the world, researchers are doing everything they can to find the most effective cure. Photopheresis has emerged as a promising treatment option for autoimmune diseases, solid organ transplant rejection, chronic graft versus host disease, and advanced cutaneous T-cell lymphoma. Currently, a few clinical trials on photopheresis therapy are being conducted to investigate its potential benefits in the treatment of autoimmune disease conditions. Photopheresis therapy for the treatment of autoimmune diseases is still in its early stages.

  The amount of time and money required to complete the treatment is enormous. This factor may make the treatment less appealing to many patients and may compel healthcare practitioners to switch to other low-cost and less time-consuming treatments, limiting the global photopheresis product overall growth prospects. Mallinckrodt Pharmaceuticals is actively conducting clinical trials on novel therapeutic indications such as Cohn's disease and multiple sclerosis conditions.

  Photopheresis is a type of apheresis and photodynamic therapy in which blood is treated with a photosensitizing agent and then exposed to specific wavelengths of light to produce an effect. WBC + platelets are separated from whole blood, chemically treated with 8-methoxy psoralen (instilled into a collection bag or given per os in advance), exposed to UVA, and returned to the patient.  Enabled 8-methoxy psoralen crosslinks DNA in cells treated, leading to nucleated cell apoptosis. After being returned to the patient, photochemically damaged T-cells appear to have cytotoxic effects on T-cell development.  The technique of such "antitumor" action is unknown.

  Government agencies are also seeing other patients receive ECP treatment to help a number of diseases by covering the costs of the treatment. Patients are being encouraged to undergo ECP therapy to treat a variety of disease conditions due to favorable reimbursement policies and the resulting coverage of medical expenses through government-supported refunds. To kill cancer cells, photodynamic therapy employs a drug that is activated by light, known as a photosensitizer or photosensitizing agent. The light can be generated by a laser or another source, such as LEDs. PDT stands for photodynamic therapy. Photodynamic therapy is most commonly used as a local treatment, meaning it only treats a specific part of the body.

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