Streptozocin; a Class of Drug Used To Treat Metastatic Islet Cell Cancer of Pancreas
Streptozocin Market Streptozocin is an anti-tumor antibiotic consisting of a nitrosourea moiety interposed between a methyl group and glucosamine. Streptozocin is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug and is classified as an alkylating agent. The United States Food and Drug Administration (FDA) approved this drug to treat pancreatic islet cells cancer. It is used to treat cancer of the pancreas that has gotten worse or spread to other parts of the body and works by slowing or stopping the growth of cancer cells in the body. Because it carries a high risk of toxicity and rarely cures cancer, its use is generally limited to patients whose cancer cannot be surgically removed. Moreover, in the medical field, it is used as a chemotherapeutic drug to treat certain cancers of the islets of Langerhans, as well as to induce diabetes in experimental animals. Streptozocin-induced diabetic models develop type 1 diabetes, due to the cytotoxic glucose analog stre...