Streptozocin; a Class of Drug Used To Treat Metastatic Islet Cell Cancer of Pancreas

https://www.coherentmarketinsights.com/ongoing-insight/streptozocin-market-2312
Streptozocin Market


  Streptozocin is an anti-tumor antibiotic consisting of a nitrosourea moiety interposed between a methyl group and glucosamine. Streptozocin is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug and is classified as an alkylating agent. The United States Food and Drug Administration (FDA) approved this drug to treat pancreatic islet cells cancer. It is used to treat cancer of the pancreas that has gotten worse or spread to other parts of the body and works by slowing or stopping the growth of cancer cells in the body.

 Because it carries a high risk of toxicity and rarely cures cancer, its use is generally limited to patients whose cancer cannot be surgically removed. Moreover, in the medical field, it is used as a chemotherapeutic drug to treat certain cancers of the islets of Langerhans, as well as to induce diabetes in experimental animals. Streptozocin-induced diabetic models develop type 1 diabetes, due to the cytotoxic glucose analog streptozotocin that is toxic to pancreatic β-cells and causes insulin deficiency.

  Streptozocin is a naturally occurring anticancer antibiotic/drug that has a mechanism of action similar to that of nitrosourea. It works by sticking to one of the DNA strands of the cancer cell so the cell can't divide into 2 new cells. However, if the patient experiences certain side effects, the doctor may need to stop or delay the treatment. Common side effects may include nausea, loss of appetite, vomiting, diarrhea, confusion, drowsiness, depression, and/or injection site reactions (burning, redness, swelling, or tenderness).

  In order to treat an infection, people should only take streptozocin under the supervision of a physician. Moreover, it is important to keep it out of the reach of children and should never share it with anyone else. Only use it for the indication that is prescribed. Streptozocin is used to treat neuroendocrine tumors, such as pancreatic islet cells tumors, and is used in combination with chemotherapy drugs such as doxorubicin and fluorouracil (5FU).

 

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