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Showing posts with the label In-situ Hybridization Market

In-Situ Hybridization; a Lab Procedure that Helps Locate Position of Specific DNA/RNA Sequences

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    In-Situ Hybridization (ISH) is a laboratory technique used to label complementary DNA, RNA, or modified nucleic acids strands. ISH helps localize specific DNA or RNA sequences in a small cross-section of tissues or an entire tissue. There are two types of in-situ hybridization, such as chromogenic in-situ hybridization (CISH) and fluorescence in situ hybridization (FISH), which are used to identify the position of genes. FISH is a laboratory-based test that can reveal the genetic makeup of cancer.   Fluorescence in-situ hybridization test can detect genetic abnormalities associated with cancer, and thus, it is useful for diagnosing some types of the disease. Thus, with the rising incidence of cancer worldwide, the demand for in-situ hybridization is also increasing at a rapid pace. Cancer is one of the leading causes of morbidity and mortality across the globe. For example, according to the American Cancer Society, in 2021, there will be an estimated 1.9 million new ...

It is known that in-situ hybridization can be used to determine the cryptologic and histological location of the nucleic acid of interest

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    Fluorescent in Situ Hybridization (FISH) Probe is a subatomic cytogenetic technique that visualizes genetic materials using fluorescent probes. These probes are molecules that absorb a specific wavelength of light and emit light when they bind to a specific DNA/RNA sequence. They are used to detect structural and numerical chromosomal abnormalities, monitor therapeutic drugs, and identify rare genetic diseases. FISH probes that are commonly used include locus-specific, Alphoid/centromeric repeat, and whole chromosome probes. They have several advantages, including high sensitivity and accuracy in recognizing targeted sequences, direct application to both metaphase and interphase nuclei, and accurate visualization of hybrid signals at the single-cell level.   One of the key factors driving the market growth is the increasing prevalence of various genetic and chronic disorders. Furthermore, the rising demand for In Vitro Diagnostics (IVD) testing and targeted thera...