What the Future of GLP-1 Receptor Agonist Work Looks like After Coronavirus

 

  Diabetes caused by GLP-1 agonists is the most common type of diabetes and is characterized by high levels of glucose (sugar) in the blood. Although some symptoms may be similar, it is not the same as type 1 diabetes. Diabetes drugs are GLP-1 agonists that not only improve blood sugar control but may also lead to weight loss.

  This class of drugs is known as glucagon-like peptide 1 receptor agonists or GLP-1 receptor agonists. Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are another class of medications linked to weight loss and better blood sugar control. Canagliflozin, dapagliflozin, and empagliflozin are examples. If you're actively trying to lose weight through lifestyle changes and adding one of these medications to your regimen, lowering blood sugar levels is beneficial for managing type 2 diabetes, but it's unclear how GLP-1 receptor agonist drugs cause weight loss. GLP-1s appear to help suppress appetite, according to doctors. These medications also slow the passage of food from the stomach to the small intestine. As a result, you may feel full faster and for a longer period of time, causing you to eat less.

  The drugs already mentioned are intended for people with type 2 diabetes. Saxenda, a drug containing a higher dose of liraglutide, is also approved for the treatment of obesity in people who do not have diabetes. GLP-1 and SGLT-2 inhibitors appear to have additional significant benefits in addition to helping to control blood sugar and boost weight loss. Some drugs in these classes of medications, according to research, may reduce the risk of heart disease, including heart failure, stroke, and kidney disease. People taking these medications have seen improvements in their blood pressure and cholesterol levels, though it is unclear whether these improvements are due to the medication.

   If you have a personal or family history of medullary thyroid cancer or multiple endocrine neoplasias, you should avoid the GLP-1 class of drugs. Laboratory studies have linked these drugs to thyroid tumors in rats, but the risk to humans is unknown until more long-term studies are completed. They are also not advised if you have had pancreatitis.

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